- Pay: $50-56/hr.
- 12-month assignment with possibility for extension or conversion based on performance and budget.
- Support computational needs for the development and validation of NGS-based assays.
- Work closely with a multi-disciplinary team of scientists and engineers to implement genomic analytical solutions for programs spanning precandidate selection through late phase clinical development.
- Develop, execute, and maintain NGS analysis pipelines for execution in cloud-based computational environments.
- Keep records of development work and testing in a GxP environment utilizing electronic notebook solutions.
- Represent the group at internal meetings.
- Degree in a relevant computer science discipline with a minimum of 3 years of relevant industry experience.
- Minimum of 1 year experience with NGS, spanning knowledge and hands-on dry-lab experience.
- Expertise in bioinformatics with a working understanding of genomic analysis solutions (e.g., FastQC, Bowtie2, SAMtools, NCBI BLAST+, Nextflow, etc.).
- Scripting experience in coding languages (e.g., bash, awk, Python, R, etc.).
- Understanding of NGS platforms, specifically those utilizing the synthesis by sequencing technique (i.e., Illumina platforms).
- Ability to work independently and adapt under aggressive and/or changing timelines.
- Familiarity with the software development lifecycle (e.g., Git).
- Automated unit testing for test driven design (TDD).
- Familiarity with basic molecular biology techniques (e.g., ligation, PCR, and qPCR) as well as nucleic acid extraction and analysis techniques (e.g., Nanodrop, DNA fragment analyzers, ddPCR, etc.).
- Knowledge of and experience with other sequencing platforms (i.e., SMRT sequencing).
- Prior experience in leading the internalization of custom NGS analysis pipelines is highly preferred.
- Wet-lab method development experience to support NGS workflows.
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