USA - Research Analyst

Cambridge, MA

The Fountain Group is currently seeking a Research Analyst for a prominent client of ours. This position is located in Cambridge, MA. Details for the position are as follows:
 
Job Description:
  • Pay: $40-51.72/hr.
  • 11-month assignment with possibility for extension or conversion based on performance and budget.
  • Prepares and optimizes pre-clinical drug formulations using appropriate technology and scientific principles for in vivo PK, Pharmacology, and safety studies
  • Conducts limited screening of known excipients, pH adjustment, etc, and chemical/physical stability check for program compounds. Prepares cassette dosing solutions for PK screening.
  • Conducts experiments and analyzes/shares data to support project progression using analytical instrumentation (HPLC, Mass Spec) to assess formulation stability and chemical stability
  • Accurately records formulation experiments/protocols in an e-notebook
  • Prepares/shares formulation protocols, technical reports, presentations, and regulatory documents as necessary
  • Ensures formulations meet IUCUC guidelines and industry standards in coordination with in vivo study director
  • Understanding and ability to implement good laboratory practices, particularly in handling preclinical pharmaceutical small molecule API for neuroscience, immunology, and oncology indications
  • Collaborates with a Global Chemistry manager, cross-functional research project teams, CROs, the Comparative Medicine group, and Pharmaceutical Science colleagues to provide project specific formulations and formulations strategies for in vivo studies (PK, efficacy, tox) 
Qualifications:
  • Bachelor’s degree in a chemistry or pharmaceutical science, or equivalent with 5+ years of experience, or Master's degree with 3+ years of experience in formulating small molecule APIs
  • Broad knowledge of acceptable excipients and equipment/instruments widely used in pre-clinical formulation preparation
  • Demonstrates technical knowledge of formulations and pharmaceutics of small molecule APIs including:
    • Solubilizing/solution formulations
    • Solid/suspension formulations
  • Well-versed in analytical instrumentation (HPLC, Mass Spec) to assess:
    • Formulation stability (physical)
    • Chemical stability
If you are interested in hearing more about the position, please respond to this posting with your resume attached.
Please forward this posting to any friends or colleagues as we do offer a Referral Bonus for any candidate hired.
 
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