siRNA Research Associate

Lexington, MA

Currently I have an opening for 2 Research Associates located in Lexington, MA. Details for the position are as follows:
 
Pay Range: $25-$43/hour (Two different level positions available)

Job Description:
  • 12-month contract with the possibility of extending or converting to permanent based on performance and budget.
  • Provide technical laboratory research effort in support of multiple projects focused on expedited evaluation and the clinical translation of therapies.
  • Execution of siRNA tool compound screenings and structure activity relationship studies
  • Cellular and molecular biology methodologies, e.g., mammalian cell culture; cell-based assays; RNA extraction and RT-qPCR; protein extraction and western blots, ELISAs and MSD assays; histological based assays including standard stains, immuno-histochemistry and in situ hybridization
  • In vivo drug candidate testing (e.g., mouse dosing (SC and IV); necropsy; sample analysis)
  • Analyze data and present the results in group meetings
  • Maintain clear experimental records in laboratory notebooks; write SOPs and other technical reports as needed
  • Work closely with research team members to quickly and effectively address critical questions related to the efficacy of our drugs
Qualifications:
  • Associates degree with 1-3 years of minimum relevant technical experience (LEVEL I), BS/BA with 3-4 years of relevant drug discovery laboratory experience in pharma industry (LEVEL II)
  • Previous experience in cellular and molecular biology is essential (e.g., quantitative real-time PCR, western blots) is required
  • Proficiency in animal handling, dosing, and necropsy is desired
  • Experience with flow cytometry or cell sorting is advantageous
  • Candidate must have strong oral and written communication skills, strong work ethics and demonstrated to be an effective contributor to group projects in a team-oriented environment
  • The ability to perform and interpret experiments reliably, and to advance projects aggressively towards defined goals is expected
 #LI-HO1

 

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